Azathioprine


Azathioprine inhibits purine synthesis. Purines are needed to produce DNA and RNA. By inhibiting purine synthesis, less DNA and RNA are produced for the synthesis of white blood cells, thus causing immunosuppression. Azathioprine is converted within tissues to 6-mercaptopurine (6-MP)

indications
Organ Transplant Rejection

specifications
USP/BP/Ph. Eur.

regulatory status
DMF / CEP

Therapeutic Focus
Nephrology

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